With ever increasing popularity, the kratom tree has become a unique household plant with an enthusiastic following. Update June 29, 2018: The U.S. Food and Drug Administration (FDA) has completed its investigation of illnesses in several states caused by Salmonella in kratom. Kratom comes with a risk of tolerance, dependence, and withdrawal Kratom users can build tolerance , or needing more to achieve the desired effect, and experience symptoms of withdrawal when they stop taking the drug.
The aim of the present study was to study this new phenomenon by (i) reviewing the state of the art on kratom pharmacology and identification; (ii) providing a comprehensive overview of kratom use cross-culturally, ranging from its traditional use in native societies in Southeast Asia to its more recent diffusion as a NPS in Western countries; (iii) exploring the subjective experience of users; (iv) identifying risks and side-effects related to its consumption.
The presence of other alkaloids like Corynanthiedine (an opiate antagonist) safeguards users from the side effects associated with opiate use. Yusoff NHM, Suhaimi FW, Vadivelu RK, et al. Abuse Potential and Adverse Cognitive Effects of Mitragynine (Kratom). Of course, people who are using wholesale kratom to overcome a preexisting opiate addiction may need to use kratom daily to avoid opiate withdrawal.
Kratom is currently listed by the Drug Enforcement Agency (DEA) as a drug of concern,” and has not been approved for any medical use by the Federal Drug Administration (FDA). Antinociceptive Action of Isolated Mitragynine from Mitragyna Speciosa through Activation of Opioid Receptor System, International Journal of Molecular Sciences, 13(9), 11427-11442.
Alex Eriksson is the founder of Epic Kratom, a blog dedicated to all Kratom lovers that provide honest and research-backed advice on how people can treat their chronic health problems using Kratom. Yellow Bali Kratom is one of the most popular yellow vein varieties because of the wide availability of Bali speciosa trees.